A bizarre series of suicides by elderly women in England raises the eyebrow of newly promoted Chief Inspector David Bliss, who soon discovers that all the women had recently sent large sums of money to a Western Union account in Vancouver. As Bliss uncovers the truth behind the deaths, old friends Daphne Lovelace and Trina Button are on a road trip through North America, raising funds to help those in need of kidney transplants. But when their fabulous Kidneymobile is found unoccupied with no trace of them, a perplexed Bliss searches frantically for his friends, and the astonishing secret that links their disappearances with the suicides.